Table 2 The detailed information on the therapeutic protocol used in patients

From: A novel analytical model of MGMT methylation pyrosequencing offers improved predictive performance in patients with gliomas

  

Total

Anaplastic Oligo, IDH-mutant, 1p/19q codeletion

Anaplastic Astro, IDH-mutant

Anaplastic Astro, IDH-wildtype

Glioblastoma, IDH-mutant

Glioblastoma, IDH-wildtype

Anaplastic Astro, NOSa

Glioblastoma, NOSa

 

TMZb cycles

200

8 (4%)

34 (17%)

30 (15%)

28 (14%)

84 (42%)

9 (5%)

7 (4%)

RT + TMZc→TMZ cycles

3–5

36 (18%)

1

6

4

7

14

3

1

 

6

154 (77%)

6

25

25

21

66

5

6

 

7–12

7 (4%)

3

4

Only TMZ

3–5

2 (1%)

1

1

 

6

1 (1%)

1

 

7–12

  1. RT: focal radiotherapy 60 Gy in 6 weeks to tumor volume + 2–3 cm margin
  2. TMZ temozolomide
  3. aNOS refers to the IDH status is lacking. And the 1p/19q of these gliomas are non-codeletion in this study
  4. b150–200 mg/m2 daily x 5 days per 28 days (1 cycle)
  5. c75 mg/m2 daily during RT