Table 3 Optimal cut-off value for each individual CpG

CpG sites	Cut-off value	AUC	Standard error	P	95% confidence interval		Sensitivity	Specificity
CpG sites	Cut-off value	AUC	Standard error	P	Lower	Upper	Sensitivity	Specificity
75	16	0.693	0.060	0.002	0.576	0.809	71%	68%
78	4	0.682	0.060	0.004	0.566	0.799	76%	60%
81	11	0.678	0.060	0.006	0.560	0.797	68%	68%
82	15	0.674	0.061	0.007	0.554	0.793	65%	70%
76	12	0.673	0.060	0.007	0.555	0.791	71%	64%
77	10	0.659	0.062	0.013	0.538	0.781	56%	76%
80	15	0.659	0.062	0.014	0.538	0.780	62%	70%
79	5	0.644	0.062	0.026	0.522	0.765	65%	64%

AUC area under the curve of the receiver operating characteristic curve analysis

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