Table 4 Effect of PTEN status on tumor-associated immune cell infiltrates
Variable | Tumor PTEN negative (59/132; 45%) | Tumor PTEN positive/heterogeneous (73/132; 55%) | p-Value |
|---|---|---|---|
CD3 (mean cells/mm2, SD) | |||
Overall | 879 (556) | 899 (575) | 0.967 |
Hotspot | 1466 (777) | 1454 (868) | 0.714 |
Periphery | 908 (575) | 900 (678) | 0.517 |
Center | 846 (588) | 879 (562) | 0.643 |
CD8 (mean cells/mm2, SD) | |||
Overall | 462 (411) | 495 (464) | 0.969 |
Hotspot | 781 (596) | 803 (631) | 0.998 |
Periphery | 507 (472) | 526 (500) | 0.844 |
Center | 413 (404) | 464 (481) | 0.912 |
CD68 (mean cells/mm2, SD) | |||
Overall | 194 (159) | 163 (119) | 0.332 |
Hotspot | 324 (232) | 274 (196) | 0.175 |
Periphery | 182 (144) | 156 (130) | 0.219 |
Center | 204 (182) | 175 (137) | 0.560 |
