Fig. 1 | Modern Pathology

Fig. 1

From: Detection of driver mutations in BRAF can aid in diagnosis and early treatment of dedifferentiated metastatic melanoma

Fig. 1

a (×400, H&E): Representative microscopic image of the scalp lesion of patient 5 showing atypical melanocytes arranged in nests and single pagetoid cells consistent with a diagnosis of melanoma. b (×400, H&E): Representative microscopic image of the lung mass identified 5 years later showing a poorly differentiated spindle cell neoplasm. c (×400, S100) and d (×400, Melan-A): Both stains are negative in tumor cells from the lung mass. Mutational testing for BRAF identified the V600E mutation in both specimens

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