Table 1 Clinicopathological characteristics

From: T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers

 

Total

MMR proficient

MMR deficient

p value

N = 76 (%)

N = 53 (%)

N = 23 (%)

Age

 <65 years

42 (55)

29 (55)

13 (57)

1.0000a

 ≥65 years

34 (45)

24 (45)

10 (44)

 

Race

 White

59 (78)

40 (76)

19 (83)

0.7623a

 Black

16 (21)

12 (23)

4 (17)

 

 (Other)

1 (1)

1 (2)

0 (0)

 

Parity

 Nulliparous

17 (22)

10 (19)

7 (30)

0.3710a

 Multiparous

58 (78)

42 (81)

16 (70)

 

 (Unknown)

1 (1)

1 (1)

0 (0)

 

Menstrual state

 Pre-menopausal

11 (15)

9 (17)

2 (9)

0.7140a

 Post-menopausal

65 (86)

44 (83)

21 (91)

 

Body mass index

 <25 kg/m2

15 (20)

11 (21)

4 (17)

0.7548a

 ≥25 kg/m2

48 (63)

31 (56)

17 (74)

 

 (Unknown)

13 (17)

11 (21)

2 (9)

 

Smoking history

 Never smoker

58 (76)

38 (72)

20 (87)

0.3610a

 Current or former smoker

15 (20)

12 (23)

3 (13)

 

 (Unknown)

3 (4)

3 (6)

0 (0)

 

Histology

 Endometrioid

60 (79)

38 (72)

22 (96)

0.0291a

 Non-endometrioid

16 (21)

15 (28)

1 (4)

 

Histology grade

 Low (G1, G2)

48 (63)

34 (64)

14 (61)

0.8008a

 High (G3)

28 (37)

19 (36)

9 (39)

 

Myometrial invasion

 Absent

23 (30)

17 (32)

6 (26)

0.7867a

 Present

53 (70)

36 (67)

17 (74)

 

Lymphovascular space invasion

 Absent or unknown

60 (79)

45 (85)

15 (65)

0.0692a

 Present

16 (21)

8 (15)

8 (35)

 

FIGO 2009 stage

 I

54 (71)

36 (68)

18 (78)

0.4967b

 II

5 (7)

5 (9)

0 (0)

 

 III

11 (15)

8 (15)

3 (13)

 

 IV

6 (8)

4 (8)

2 (9)

 

Estrogen receptor

 Negative

1 (1)

1 (2)

0 (0)

1.0000a

 Positive

75 (99)

52 (98)

23 (100)

 

Progesterone receptor

 Negative

7 (9)

5 (9)

2 (9)

1.0000a

 Positive

69 (91)

48 (90)

21 (91)

 

ARID1A

 Retain

50 (66)

42 (79)

8 (35)

0.0004a

 Loss

26 (34)

11 (21)

15 (65)

 

Tumor PD-L1, case no.

 Negative

53 (70)

42 (79)

14 (61)

0.1546a

 Positive

23 (30)

11 (21)

9 (39)

 
  1. aFisher’s exact test
  2. bWilcoxon test