Table 5 Correlations between PD-L1 Tumor Proportion Score and genetic alterations identified by next generation sequencing in 86 cases

From: Programmed death ligand-1 expression in non-small cell lung cancer in a Western Australian population and correlation with clinicopathologic features

 

No. of cases n = 86

PD-L1 < 50% n = 61 (71%)

PD-L1 ≥ 50% n = 25 (29%)

p-value

 

N (%)

TP53

Positive

40 (47)

28 (70)

12 (30)

0.52

 

Negative

46 (53)

33 (72)

13 (28)

 

Other mutations

    
 

BRAF

4

3 (75)

1 (25)

 
 

MET

4

4 (100)

0 (0)

 
 

PIK3CA

3

1 (33)

2 (67)

 
 

STK11

3

3 (100)

0 (0)

 
 

APC

2

1 (50)

1 (50)

 
 

CTNNB1

2

2 (100)

0 (0)

 
 

PTEN

2

2 (100)

0 (0)

 
 

MAP21K

1

1 (100)

0 (0)

 
 

SMAD4

1

1 (100)

0 (0)

 
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