Table 2 Clinicopathological features of 10 angiosarcomas and 22 anaplastic carcinomas of the thyroid

From: Angiosarcoma and anaplastic carcinoma of the thyroid are two distinct entities: a morphologic, immunohistochemical, and genetic study

 

Sex

Age at surgery

Prevalent histological pattern

Well-differentiated component

Site of metastases

Treatment

Follow-up, months

Angiosarcomas

 1

M

57

Epithelioid

  

Thyroidectomy

NA

 2

M

66

Epithelioid

 

Bone (femur)

Thyroidectomy,

DOD, 5

 3

M

71

Sarcomatoid

 

Neck

Thyroidectomy,

DOD, 5

 4

M

75

Sarcomatoid

 

Bone (femur)

hyroidectomy

NA

 5

M

73

Epithelioid

 

Neck, lung

Thyroidectomy

DOD, 11

 6

F

52

Epithelioid

 

Mediastinum

Thyroidectomy, chemotherapy

DOD, 9

 7

F

91

Epithelioid

 

Neck

Thyroidectomy

DOD, 2

 8

F

71

Epithelioid

  

Thyroidectomy

NA

 9

M

74

Sarcomatoid

 

Lung

Thyroidectomy, chemotherapy

AWD, 66

 10

F

68

Sarcomatoid

  

Throidectomy

NA

Anaplastic carcinomas

 1

M

72

Squamoid

  

Thyroidectomy

NA

 2

M

58

Sarcomatoid

Papillary carcinoma, tall cell variant

 

Thyroidectomy

NA

 3

M

67

Pleomorphic epithelioid

Classic papillary carcinoma

 

Thyroidectomy

DOC, 78

 4

F

74

Sarcomatoid

  

Thyroidectomy

NA

 5

F

84

Pleomorphic epithelioid with giant cells

Papillary carcinoma, tall cell variant

 

Thyroidectomy

NA

 6

M

39

Pleomorphic epithelioid

Hürthle cell carcinoma

 

Thyroidectomy

NA

 7

M

59

Pleomorphic epithelioid

Papillary carcinoma, tall cell variant

 

Thyroidectomy

DOD, 1

 8

F

70

Pleomorphic epithelioid with giant cells

Hürthle cell carcinoma

 

Thyroidectomy

DOD, 1

 9

F

73

Pleomorphic epithelioid

Papillary carcinoma, follicular variant

 

Thyroidectomy

DOC, 194

 10

M

69

Sarcomatoid

Papillary carcinoma, follicular variant

 

Thyroidectomy

DOD, 2

 11

F

52

Sarcomatoid

Hürthle cell carcinoma

 

Thyroidectomy

DOC, 100

 12

F

63

Pleomorphic epithelioid with giant cells

 

Lung

Thyroidectomy

DOD, 1

 13

F

65

Sarcomatoid

 

Neck, mediastinum

Thyroidectomy

DOD, 1

 14

M

47

Pleomorphic epithelioid

Hürthle cell carcinoma

Lung, pleura, lymph nodes

Thyroidectomy, radiotherapy, chemotherapy

DOD, 22

 15

M

80

Pleomorphic epithelioid with giant cells

 

Lung, neck

Thyroidectomy, radiotherapy

DOD, 2

 16

F

82

Sarcomatoid with giant cells

 

Lung,

Thyroidectomy

DOD, 2

 17

M

78

Squamoid

Papillary carcinoma, tall cell variant

Lung, pleura, bone, lymph nodes

Thyroidectomy

DOD, 4

 18

M

74

Squamoid

 

Neck, oropharynx, lymph nodes

Thyroidectomy, radiotherapy

DOD, 9

 19

F

63

Pleomorphic epithelioid

  

Thyroidectomy, radiotherapy, radiometabolic therapy

ANED, 88

 20

F

84

Sarcomatoid

Papillary carcinoma,columnar cell variant

Lung, lymph nodes, bone

Thyroidectomy, radiotherapy

DOD, 3

 21

F

74

Sarcomatoid

  

Thyroidectomy

NA

 22

F

56

Pleomorphic epithelioid

 

Lung, lymph nodes

Thyroidectomy

DOD, 3

  1. NA not available, DOD dead of disease, DOC dead of other causes, AWD alive with disease, ANED alive with no evidence of disease