Fig. 4 | Modern Pathology

Fig. 4

From: Characteristics of mismatch repair deficiency in sarcomas

Fig. 4

Unclassified sarcoma arising within the deltoid muscle of a 64-year old man (a) with MSH6 mutation and loss of MSH6 expression (b), showing PD-L1 expression in macrophages at the tumor-stroma interface (c). Immunohistochemistry for P53 showed aberrant diffuse strong nuclear positivity (d), consistent with the presence of a TP53 c.818 G > A nonsense mutation

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