Fig. 5 | Modern Pathology

Fig. 5

From: Detection of DNA damage response in nonalcoholic fatty liver disease via p53-binding protein 1 nuclear expression

Fig. 5

Caspase-independent expression of p53-binding protein 1 (53BP1) in palmitate-treated hepatocytes. Data are expressed as the means ± SEM. *p < 0.05. a Caspase activity assay in clone 9 rat hepatocytes after treatment with 100 μM palmitate for 24 h. b Cells were treated with 100 μM palmitate in presence or absence of caspase inhibitor zVad-fmk (10 μg/mL). Rate of abnormal 53BP1 foci -expressing cells was quantified. Data are expressed as the means ± SEM. *p < 0.05

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