Table 2 Univariate and multivariate analyses of prognostic factors for all-stage endometrial endometrioid carcinoma

From: Impact of TP53 immunohistochemistry on the histological grading system for endometrial endometrioid carcinoma

 

Univariate analysis (progression-free survival)

Multivariate analysis (progression-free survival)

Univariate analysis (overall survival)

Multivariate analysis (overall survival)

Variables

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

p-value

HR

95% CI

p-value

Age (<60 vs. ≥60 years)

1.74

1.12–2.72

0.015

   

1.62

1.00–2.62

0.049

   

TP53 status (normal vs. aberrant)

3.88

2.49–6.07

<0.001

   

4.31

2.67–6.95

<0.001

   

FIGO grade (G1/2 vs. G3)

1.96

1.55–2.49

<0.001

   

2.14

1.67–2.74

<0.001

   

Prognostic grade (low vs. high)

4.67

3.01–7.23

<0.001

2.91

1.85–4.56

<0.001

5.34

3.31–8.62

<0.001

3.62

2.21–5.94

<0.001

FIGO stage (I/II vs. III/IV)

3.43

2.72–4.33

<0.001

3.06

2.41–3.89

<0.001

3.20

2.49–4.11

<0.001

2.83

2.19–3.66

<0.001

  1. HR hazard ratio, CI confidence interval, BMI body mass index, FIGO International Federation of Gynecology and Obstetrics