Table 2 Univariate and multivariate analysis for time to death from prostate cancer in a conservatively managed needle biopsy cohort

From: Ki-67 is an independent predictor of prostate cancer death in routine needle biopsy samples: proving utility for routine assessments

Variable

Univariate

Multivariate

IQRa HR (95%CI)

LR χ12

p-value

c-indexb

IQRa HR (95%CI)

LR χ12c

p-value

Grade group

1.68 (1.50, 1.89)

74.56

<2.2a10−16

0.716

1.38 (1.20, 1.59)

74.56

<2.2a10−16

Ki-67 (continuous)

1.68 (1.49, 1.89)

47.97

4.3a10−12

0.665

134 (1.16, 1.54)

19.85

8.38a10−06

Extent

3.21 (2.35, 4.38)

59.96

97a10−15

0.690

1.74 (1.21, 2.50)

14.29

0.0002

PSA

1.66 (1.43, 1.93)

36.90

1.24a10−09

0.660

1.16 (0.98, 1.38)

2.77

0.096

Age

1.17 (0.93, 1.47)

1.81

0.178

0.527

   

LR χ 4 2 ( p -value)

 

111.469 (<2e-16)

c-index b (95%CI)

0.757 (0.707, 0.808)

  1. aInterquartile-range hazard ratios for continuous predictors and simple hazard ratios for categorical predictors
  2. bHarrell’s c-index
  3. cTerms added sequentially (first to last)
Back to article page