Table 1 Comparison of genomic changes in atypical hepatocellular neoplasms with and without atypia

From: Genomic profiling of well-differentiated hepatocellular neoplasms with diffuse glutamine synthetase staining reveals similar genetics across the adenoma to carcinoma spectrum

Genomic changes

AHN without atypia (n = 7)

AHN with atypia (n = 6)

p value

CTNNB1 mutation or in-frame deletion

6 (86)

3 (50)

0.164

Other Wnt pathway mutations

1 (14)

0

0.335

Mutations involving genes other than Wnt pathway

3 (43)

3 (50)

0.797

Copy number alterations

1 (14)

3 (50)

0.164

  1. Figures in parenthesis reflect percentages
  2. AHN atypical hepatocellular neoplasm