Table 2 Comparison of genomic changes in atypical hepatocellular neoplasms and hepatocellular carcinomas

From: Genomic profiling of well-differentiated hepatocellular neoplasms with diffuse glutamine synthetase staining reveals similar genetics across the adenoma to carcinoma spectrum

Genomic changes

AHN (n = 13)

HCC (n = 14)

p value

CTNNB1 mutation or in-frame deletion

9 (69)

12 (86)

0.303

Other Wnt pathway mutations

1 (8)

1 (7)

0.957

Mutations involving genes other than Wnt pathway

6 (46)

7 (50)

0.842

TERT promoter mutation

0

3 (21)

0.077

Copy number alterations

4 (31)

9 (64)

0.082

  1. Figures in parenthesis reflect percentages
  2. AHN atypical hepatocellular neoplasm, HCC hepatocellular carcinoma
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