Table 2 Clinicopathological characteristics (n = 473)
From: Ductal carcinoma in situ of the breast: immune cell composition according to subtype
Age at diagnosis (in years) | |
- Median (range) | 58 (27–84) |
Surgery (%) | |
- Breast-conserving surgery | 293 (62) |
- Mastectomy | 180 (38) |
Diameter (in cm) | |
- Median (range) | 2.00 (0.1–23.0) |
- Missing (n) | 65 |
Growth pattern (%) | |
- Solid | 239 (51) |
- Cribriform | 190 (40) |
- Micropapillary | 37 (8) |
- Papillary | 7 (1) |
Grade (%) | |
- Low | 63 (13) |
- Intermediare | 166 (35) |
- High | 244 (52) |
Calcification (%) | |
- Absent | 134 (28) |
- Present | 339 (72) |
Comedonecrosis (%) | |
- Absent | 234 (49) |
- Present | 239 (51) |
TILs density (%) | |
- Minimal | 212 (45) |
- Mild | 110 (23) |
- Moderate | 113 (24) |
- Severe | 38 (8) |
TILs distribution (%) | |
- Focal | 71 (15) |
- Patchy | 133 (28) |
- Diffuse | 57 (12) |
- N.A. | 212 (45) |
Immunohistochemical subtype (%) | |
- ER+PR±HER2− | 255 (54) |
- ER+PR±HER2+ | 80 (17) |
- ER−PR−HER2+ | 85 (18) |
- ER−PR−HER2− | 22 (5) |
- Missing | 31 (7) |
Ipsilateral recurrence (%) | |
- None | 450 (95) |
- Ductal carcinoma in situ | 4 (1) |
- Invasive breast cancer | 5 (1) |
- Invasive breast cancer and metastasis | 5 (1) |
- Metastasis | 2 (0) |
- Missing | 7 (2) |
