Table 2 Clinicopathologic and histologic characteristics and the expression of VISTA and PD-L1 by immunohistochemistry in MPM TMA cohort
Overall n = 319 | Epithelioid n = 254 | Biphasic n = 41 | Sarcomatoid n = 24 | p-value* | |
|---|---|---|---|---|---|
VISTA raw score, median (range) | 50 (0 to 100) | 50 (0 to 100) | 20 (0 to 95) | 0 (0 to 50) | <0.001 |
PD-L1 raw score, median (range) | 0 (0 to 95) | 0 (0 to 95) | 0 (0 to 95) | 20 (0 to 95) | <0.001 |
Age, median (range) | 64 (29 to 85) | 63 (29 to 85) | 66 (41 to 79) | 66 (46 to 78) | 0.016 |
Female, n (%) | 82 (25.7) | 72 (28.3) | 5 (12.2) | 5 (20.8) | 0.073 |
Stage, n (%) | |||||
1 | 10 | 10 | 0 | 0 | 0.023 |
2 | 75 | 67 | 4 | 4 | |
3 | 187 | 147 | 27 | 13 | |
4 | 47 | 30 | 10 | 7 |
