Table 6 Salient clinical and histologic features of microcystic adnexal carcinoma

From: Do not break a sweat: avoiding pitfalls in the diagnosis of sweat gland tumors

Microcystic adnexal carcinoma

Clinical features

Histologic features

Indurated plaques

Head

Middle-aged to elderly adults

Locally destructive growth

Risk for local recurrence

Diffusely infiltrative

Dermal based with invasion of subcutis

Bland basaloid cords and strands in desmoplastic stroma

Keratocyst formation and calcifications

Ductal differentiation

Little cytologic atypia, scant mitoses

Perineural infiltration