Table 2 Based on the histopathological evaluation, all patients (n = 51) were divided into two groups: chronic sclerosing sialadenitis or non-sclerosing chronic sialadenitis. This table summarizes the histopathological and immunohistological findings in chronic sclerosing sialadenitis and non-sclerosing chronic sialadenitis
Chronic sclerosing sialadenitis | Non-sclerosing chronic sialadenitis | |||
|---|---|---|---|---|
n = 34 | % | n = 17 | % | |
H&E-staining | ||||
Associated sialolithiasis | 11 | 32 | 8 | 47 |
Dense lymphoplasmacytic infiltrate | 29 | 85 | 11 | 65 |
Germinal centers with lymphoid follicles | 29 | 85 | 9 | 53 |
Fibrosis: storiform | 20 | 58 | 6 | 35 |
Fibrosis: dense | 28 | 82 | 15 | 88 |
Eosinophilic infiltrate | 1 | 3 | 1 | 6 |
IgG4-staining | ||||
≥70 IgG4 + plasma cells/HPF | 8 | 24 | 4 | 24 |
Additional IgGa and CD31b staining | n = 8 | % | n = 4 | % |
IgG4/IgG-plasma cell ratio ≥40% | 3 | 38 | 3 | 75 |
Obliterative phlebitis | 1 | 13 | 2 | 50 |