Fig. 3 | Modern Pathology

Fig. 3

From: Acute myeloid leukemia with isolated del(5q) is associated with IDH1/IDH2 mutations and better prognosis when compared to acute myeloid leukemia with complex karyotype including del(5q)

Fig. 3

Heat map demonstrating the mutational profile of acute myeloid leukemia cases with isolated del(5q) and acute myeloid leukemia cases with complex karyotype including del(5q). Acute myeloid leukemia with isolated del(5q) showed higher percentage of IDH1/IDH2 mutations (p < 0.01), while acute myeloid leukemia with complex karyotype including del(5q) showed higher percentage of TP53 mutations (p < 0.01). Acute myeloid leukemia cases with complex karyotype also demonstrated frequent chromosome 7 abnormalities and del(17p)

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