Table 2 Clinic-pathologic features of cases diagnosed as postpubertal-type teratoma based on morphology and immunochemistry without molecular investigation (except case 35 which underwent molecular testing)
Case no. | Age | Size (mm) | Histologic findings | Germ cell neoplasia in situ | Regression/ atrophy | Remarks |
|---|---|---|---|---|---|---|
15 | 19 | 10 | Cartilage, glands | Yes | Yes | |
16 | 27 | 45 | Squamous epithelium with atypia and glands | Yes | Yes | |
17 | 38 | 6 | Squamous epithelium, immature glands, and cartilage | No | Yes | |
18 | 23 | 45 | Squamous epithelium, glands, cartilage, and smooth muscle | Yes | Yes | |
19 | 21 | 18 | Glands with atypia, cartilage | Yes | Yes | |
20 | 52 | 75 | Primitive neuroectodermal tumor 75%, glands and smooth muscle | No | Yes | |
21 | 26 | 55 | Glands, fibrous tissue | NA | NA | Presentation with metastasis |
22 | 43 | 13 | Glands with atypia, smooth muscle, cartilage | No | Yes | |
23 | 28 | 90 | Cartilage, focal ganglioneural tissue | NA | NA | Presentation with metastasis |
24 | 67 | 14 | Squamous epithelium, glands with atypia and cartilage | Yes | Yes | |
25 | 54 | 60 | Squamous epithelium and immature glands | No | Yes | |
26 | 29 | 46 | Cartilage, glands, bone, and smooth muscle | Yes | Yes | |
27 | 27 | NA | Glands and smooth muscle | Yes | Yes | Partial orchiectomy |
28 | 33 | 42 | Glands, squamous epithelium, glia, cartilage | No | Yes | |
29 | 32 | 12 | Squamous epithelium, bone | No | Yes | |
30 | 35 | 13 | Squamous epithelium, glands, and smooth muscle | Yes | Yes | |
31 | 28 | 70 | Glands, smooth muscle, squamous epithelium | Yes | Yes | Presentation with metastasis |
32 | 22 | 75 | Glands and necrotic areas | No | No | Widespread necrosis in the testicular tumor |
33 | 59 | NA | Glands, smooth muscle | No | Yes | |
34 | 30 | 60 | Primitive neuroectodermal tumor 5%, mature elements | Yes | Yes | |
35 | 46 | 7 | Skeletal muscle only | No | No | 12p amplification |
