Table 3 Association of atrial amyloidosis with preoperative and post-Maze atrial arrhythmia status

From: Amyloidosis in surgically resected atrial appendages: a study of 345 consecutive cases with clinical implications

 

Total

Amyloid (−) (n = 185)

Amyloid (+) (n = 160)

p value

Odd ratio (95%CI; p value)

Age- and sex-adjusted

p value

OR (95%CI)

Preoperative

AA status (n = 335)

0.0088

2.51 (1.2–5.1; 0.0160)

0.0225

2.41 (1.3–5.1)

 AAd

293 (87%)

146 (50%)

147 (50%)

    

 SR

42 (13%)

30 (71%)

12 (29%)

    

AF status (n = 312)

0.0053

2.63 (1.3–5.3; 0.0076)

0.0175

2.40 (1.1–5.1)

 AF

271 (87%)

132 (49%)

139 (51%)

    

 SR

42 (13%)

30 (71%)

12 (29%)

    

AF pattern (n = 252e)

0.0017

2.41 (1.4–4.2; 0.0019)

0.0001

2.44 (1.3–4.4)a

 Persistent

178 (71%)

72 (40%)

106 (60%)

    

 Paroxysmal

74 (29%)

46 (62%)

28 (38%)

    

>3 months post-Maze recurrence of arrhythmia

AA recurrence in cases with pre-op AA (n = 123f)

0.0073

2.93 (1.3–6.5; 0.0083)

0.0380

2.51 (1.05–6.0)b

 Yes

82 (67%)

37 (45%)

45 (55%)

    

 No

41 (33%)

29 (71%)

12 (29%)

    

AF recurrence in cases with pre-op AF (n = 93g)

0.0020

3.86 (1.6–9.3; 0.0024)

0.1100

3.25 (1.3–8.0)c

 Yes

52 (56%)

20 (38%)

32 (62%)

    

 No

41 (44%)

29 (71%)

12 (29%)

    
  1. AA atrial arrhythmia of any type, AF atrial fibrillation, pre-op preoperative, SR sinus rhythm
  2. aFor persistent atrial fibrillation
  3. bFor atrial arrhythmia recurrence
  4. cFor atrial fibrillation recurrence
  5. dOf 293 cases where preoperative atrial arrhythmias status was available, 271 cases had atrial fibrillation, 16 had typical atrial flutter and 6 cases had atrial tachycardia
  6. eOf 271 cases with preoperative atrial fibrillation, pattern of atrial fibrillation was accessed/available in 252 cases
  7. fThese 123 cases are those where Maze procedure was performed, and they had preoperative history of any type of atrial arrhythmia. Please note 98 of total 345 did not have Maze or other arrhythmia related surgery; appendages were removed during other surgeries such as CABG or MV surgery etc
  8. gThese 93 cases are those where Maze procedure was performed AND they had preoperative history of atrial fibrillation
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