Table 1 Cyclin D1 scores (as % staining)
From: Cyclin D1 immunohistochemical staining to separate benign from malignant mesothelial proliferations
Score | 0 | 1–25% | 26–50% | 51–75% | 76–100% | N |
|---|---|---|---|---|---|---|
Tissue microarray 1 | ||||||
Reactive epithelial proliferations | 10 | 6 | 0 | 0 | 0 | 16 |
Reactive spindle cell proliferations | 4 | 8 | 3 | 0 | 0 | 15 |
Epithelial malignant mesotheliomas | 5 | 5 | 2 | 3 | 12 | 27 |
Sarcomatous/desmoplastic malignant mesotheliomas | 1 | 1 | 1 | 1 | 4 | 8 |
Tissue microarray 2 | ||||||
Reactive epithelial proliferations | 32 | 4 | 0 | 0 | 0 | 36 |
Reactive spindle cell proliferations | 14 | 19 | 2 | 1 | 0 | 36 |
Epithelial malignant mesotheliomas | 1 | 4 | 6 | 6 | 10 | 27 |
Sarcomatous/desmoplastic malignant mesotheliomas | 4 | 4 | 0 | 0 | 6 | 14 |
Combined tissue microarrays | ||||||
Reactive epithelial proliferations | 42 | 10 | 0 | 0 | 0 | 52 |
Reactive spindle cell proliferations | 18 | 27 | 5 | 1 | 0 | 51 |
Epithelial malignant mesotheliomas | 6 | 9 | 8 | 9 | 22 | 54 |
Sarcomatous/desmoplastic malignant mesotheliomas | 5 | 5 | 1 | 1 | 10 | 22 |