Fig. 1: Schematic representation of the cases included and analyses conducted in this study. | Modern Pathology

Fig. 1: Schematic representation of the cases included and analyses conducted in this study.

From: Immunohistochemical analysis of IDH2 R172 hotspot mutations in breast papillary neoplasms: applications in the diagnosis of tall cell carcinoma with reverse polarity

Fig. 1

Depiction of the cases evaluated in this study, encompassing breast papillary lesions including tall cell carcinomas with reverse polarity (n = 14), intraductal papillomas (n = 13), solid papillary carcinomas (n = 16), and encapsulated papillary carcinomas (n = 5) subjected to Sanger sequencing analysis of the IDH2 R172 hotspot locus and of exons 9 and 20 of PIK3CA, and to the immunohistochemical analysis for IDH2 R172 (clone 11C8B1). Triple-negative breast cancers (n = 226) were subjected to immunohistochemical analysis of IDH2 R172 expression using tumor microarrays.

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