Table 1 SHG parameters definition.
From: Prognostic value of desmoplastic stroma in intrahepatic cholangiocarcinoma
Analysis type | Output | Acronym | definition |
|---|---|---|---|
Collagen intensity | Collagen area ratio | CAR | Relative amount of collagen compared to the total region of interest |
Saturated collagen area ratio | SCAR | Area of collagen that has pixels equal to 255 only | |
Unsaturated collagen area ratio | UCAR | Area of collagen minus the area of collagen that has saturated pixels | |
Collagen area ratio in tissue | CART | Relative amount of collagen compared to the total tissue area. | |
Saturated collagen area ratio in tissue | SCART | Relative amount of saturated collagen compared to the total tissue area. | |
Unsaturated Collagen Area Ratio per Tissue | UCART | Relative amount of unsaturated collagen compared to the total tissue area | |
Collagen fiber density | CFD | Measure of how closely packed collagen fibers are to each other (defined by the sum of all collagen pixel intensities divided by the collagen area) | |
Unsaturated collagen fiber density | UCFD | Measure of how closely packed collagen fibers are to each other (defined by the sum of all collagen pixel intensities divided by the unsaturated collagen area), where unsaturated collagen area is the area of collagen minus the area of collagen that has saturated pixels (i.e., a value of 255). | |
Collagen fiber density per tissues | CFDT | Sum of all collagen pixel intensities divided by the tissue area | |
Collagen tissue proportion | CTP | CTP is the ratio of CAR and TAR, which is equivalent to the ratio of collagen area by the tissue area. CTP = CART/100 | |
Tissue intensity | Tissue area ratio | TAR | Relative amount of tissue compared to the total region of interest. The higher this number, the more tissue there is relative to the total region of interest |
Tissue density | TD | Measure of how closely packed tissue fibers are to each other | |
Structure | Collagen reticulation index | CRI | A measure of how many collagen fiber branches there are within the entire length of the collagen network |
Collagen area reticulation density | CARD | Ratio expression of the number of branch points relative to the area of collagen. The higher the ratio, the more branches there are per unit area within the area of collagen | |
Tissue reticulation index | TRI | A measure of how many tissue fragment branches there are within the entire length of the tissue network | |
Tissue area reticulation density | TARD | Ratio expression of the number of branch points relative to the area of the tissue. The higher the ratio, the more branches there are per unit area within the area of the tissue |