Table 1 Demographic, original pathologic assignment and clinical diagnosis of patients included in this study.

From: Key histopathologic features in idiopathic noncirrhotic portal hypertension: an interobserver agreement study and proposal for diagnostic criteria

Characteristic

INCPH

(n = 34)

Non-INCPH control group 1

(n = 70)

  

INCPH mimics with original assignment of OPV

(n = 18)

Non-INCPH without original assignment of OPV

(control group 2, n = 52)

Age (mean [range]) (year)

53.6 (7–82)

50.7 (22–75)

50.8 (19–80)

Male:female

20:14

10:8

18:34

Original pathologic assignment

Consistent with OPV (n = 25)

Consistent with OPV (n = 16)

No or minimal changesa (n = 35)

 

Possible OPV (n = 9)

Possible OPV (n = 2)

Mild changesb (n = 16)

   

Steatohepatitis (n = 1)

Clinical diagnosis or biopsy indication

INCPH (n = 34)

NCPH with known etiology (n = 8)

Abnormal liver function tests (n = 18)

 

OLT before diagnosis (n = 3)

Neoplasia (n = 3)

Morbid obesity (n = 16)

 

Required OLT (n = 2)

Extrahepatic PVT (n = 2)

Donor liver harvest (n = 6)

 

Developed PVT (n = 4)

Budd-Chiari (n = 2)

Allograft liver evaluation (n = 3)

  

Primary sclerosing cholangitis (n = 1)

Cystic fibrosis (n = 2)

  

No PH (n = 10)

Primary biliary cirrhosis (n = 2)

  

ESRD with ascites (n = 1)

Hepatitis C (n = 2)

  

Chronic renal disease (n = 1)

Metastatic adenocarcinoma (n = 1)

  

Breast carcinoma with ascites (n = 1)

Gastrojejunal ulcer (n = 1)

  

Idiopathic elevation of ALP (n = 1)

Rule out Wilson disease (n = 1)

  

Constrictive pericarditis (n = 1)

 
  

Left PVT (n = 1)

 
  

Subcapsular hepatic hematoma (n = 1)

 
  

Hepatosplenomegaly (n = 1)

 
  

Hepatic steatosis (n = 1)

 
  

Thrombocythemia (n = 1)

 
  1. OLT orthotopic liver transplantation, PVT portal vein thrombosis, ESRD end-stage renal disease.
  2. aNo significant histopathologic change, minimal inflammation, minimal macrovesicular steatosis, and/or minimal fibrosis are grouped as no or minimal changes.
  3. bMild inflammation, mild macrovesicular steatosis, and/or mild fibrosis are grouped as mild changes.