Table 5 Logistic regression analysis of clinical diagnosis (INCPH versus non-INCPH control groups) against histologic features.

From: Key histopathologic features in idiopathic noncirrhotic portal hypertension: an interobserver agreement study and proposal for diagnostic criteria

Histologic feature

INCPH vs Non-INCPH control 1

INCPH vs Non-INCPH control 2

 

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

Portal vein sclerosis

OR = 8.13, 95% CI: 3.15, 20.95, p < 0.001

OR = 12.89; 95% CI: 2.42, 68.59, p = 0.003

OR = 13.65, 95% CI: 4.77, 39.03, p < 0.001

OR = 19.18; 95% CI: 3.38, 108.97, p = 0.001

Aberrant portal/periportal vessels

OR = 0.95, 95% CI: 0.42, 2.15, p = 0.897

OR = 0.62; 95% CI: 0.23, 1.69, p = 0.351

OR = 0.96, 95% CI: 0.41, 2.29, p = 0.934

OR = 0.43; 95% CI: 0.12, 1.46, p = 0.176

Increase in portal fibrous tissue

OR = 3.93, 95% CI: 1.60, 9.64, p = 0.003

OR = 0.59; 95% CI: 0.11, 3.10, p = 0.536

OR = 5.72, 95% CI: 2.20, 14.89, p < 0.001

OR = 0.87; 95% CI: 0.16, 4.63, p = 0.874

Nodular regenerative hyperplasia

OR = 1a

OR = 1a

OR = 1a

OR = 1a

  1. OR odds ratio, CI confidence interval.
  2. aRegression analysis for nodular regenerative hyperplasia failed due to lack of sufficient consensus among pathologists.
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