Fig. 2: Differential expression of miRNAs in metastatic- and nonmetastatic intramucosal carcinoma (M-IMC and N-IMC).
From: MicroRNA signatures associated with lymph node metastasis in intramucosal gastric cancer
a Principal component analysis of 16 M-IMCs, 12 N-IMCs, and 7 normal gastric mucosal tissues. b Workflow of the process for the identification of lymph node metastasis-related miRNAs. c List of upregulated miRNAs in M-IMC compared to N-IMC and normal gastric mucosal tissue with relative levels expressed in fold change. d Downregulated miRNAs in M-IMC compared to N-IMC and normal gastric mucosal tissue with relative levels expressed in fold change. e Experimental validation of altered miRNA expression in M-IMC compared to N-IMC using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR). All experiments were conducted in triplicate. Data are presented as means ± SD. Unpaired two-tailed t tests were used for statistical analysis. **p < 0.01 and *p < 0.05.
