Fig. 4: Schematic representation of TFEB gene rearrangement. | Modern Pathology

Fig. 4: Schematic representation of TFEB gene rearrangement.

From: TFEB rearranged renal cell carcinoma. A clinicopathologic and molecular study of 13 cases. Tumors harboring MALAT1-TFEB, ACTB-TFEB, and the novel NEAT1-TFEB translocations constantly express PDL1

Fig. 4

Schematic representation of RNA sequencing results showing TFEB fusion transcripts with MALAT1 (A), ACTB (B), and NEAT1 (C). Exons of TFEB and the sequencing near the breakpoint are shown in red and exons of its partner gene and the sequencing near the breakpoint are shown in blue. Arrows indicate breakpoint and its chromosomal locations are listed below.

Back to article page