Table 3 c-FOS immunohistochemistry in PF/PM and histological mimics.
From: Recurrent FOS rearrangement in proliferative fasciitis/proliferative myositis
Tumor types | N | Positive# | Comments |
|---|---|---|---|
Proliferative fasciitis/myositis | 6 | 5 | Strong staining in virtually all epithelioid cells in 5/6 cases. |
Pleomorphic sarcoma with epithelioid features | 15 | 0 | Weak to strong staining in <5% of cells in 10/15 cases. |
Epithelioid sarcoma | 10 | 0 | Weak to moderate staining in <1 to 40% of cells in 8/10 cases. |
Epithelioid hemangioendothelioma | 5 | 0 | Strong staining in 5% of cells in 1/5 cases. |
Pseudomyogenic hemangioendothelioma | 5 | 0 | Moderate staining in <1% of cells in 1/5 cases. |
Embryonal rhabdomyosarcoma | 5 | 0 | Weak to strong staining in <5% in 4/5 cases. |
Ganglioneuroma/Ganglioneuroblastoma | 5 | 0 | Weak to strong staining in ≤5% of ganglion cells in 2/5 cases. |
Nodular fasciitis | 10 | – | Weak to strong staining in <1 to 10% of spindle cells and small cells in 10/10 cases. |
