Fig. 3: TERT promoter hotspot mutations in paired primary aGCTs and recurrences. | Modern Pathology

Fig. 3: TERT promoter hotspot mutations in paired primary aGCTs and recurrences.

From: Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary

Fig. 3: TERT promoter hotspot mutations in paired primary aGCTs and recurrences.

TERT promoter hotspot mutations and their clonality identified in primary aGCTs (left) and their matched recurrences (right) using targeted MSK-IMPACT sequencing. The TERT mutations were validated by Sanger sequencing and the electropherograms of all samples are shown. Cancer cell fractions are color-coded according to the legends and clonal mutations are depicted by a yellow box. Arrows in electropherograms indicate TERT promoter mutations.

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