Table 1 Clinicopathological features of pancreatic malignancies with acinar cell differentiation (n = 30).
From: RAF1 rearrangements are common in pancreatic acinar cell carcinomas
ID | Histology | Resection | Sex | Age (years) | Size (mm) | pT | pN | pM | AJCC stage | RAF1 FISH | BRAF FISHb | RET FISHb |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ACC | Autopsy | M | 81 | 1 | 4 | Neg | Neg | Neg | |||
2 | ACC | Whipple | M | 29 | 43 | 3 | 1 | 0 | 2b | Neg | Neg | Neg |
3 | ACC | Core biopsy | F | 54 | 20 | 1 | 1 | 4 | Neg | Neg | Neg | |
4 | ACC | Core biopsy | M | 69 | 1 | 4 | Neg | Neg | Neg | |||
5 | ACC | Whipple | M | 66 | 43 | 3 | 0 | 0 | 2a | Neg | Neg | Neg |
6 | ACC | Whipple | F | 33 | 90 | 3 | 1 | 0 | 2b | Failed | Neg | Neg |
7 | ACC | Core biopsy | M | 73 | 1 | 1 | 4 | Neg | Neg | Neg | ||
8 | PB | Distal pancreas | F | 55 | 60 | 3 | 0 | 0 | 2a | Neg | Neg | Neg |
9 | ACC | Whipple | M | 79 | 30 | 2 | 0 | 0 | 1b | Pos (70% split 5’/3’ signals) | Neg | Neg |
10 | PB | Distal pancreas | F | 70 | 140 | 3 | 0 | 0 | 2a | Neg | Neg | Neg |
11 | ACC | Distal pancreas | M | 42 | 13 | 1 | 0 | 0 | Ia | Neg | Neg | Neg |
12a | ACC | Core biopsy | M | 34 | 1 | 4 | Pos (66% loss of 5’ signal) | Pos (split 5’/3’ signals) | Neg | |||
13 | ACC-NET | Core biopsy | M | 50 | 1 | 4 | Neg | Neg | Neg | |||
14 | ACC | Whipple | M | 17 | 57 | 3 | 0 | 0 | 2a | Neg | Neg | Neg |
15 | ACC | Whipple | M | 65 | 46 | 3 | 0 | 0 | 2a | Neg | Neg | Neg |
16 | ACC | Distal pancreas | F | 71 | 22 | 2 | 0 | 0 | 1b | Neg | Neg | Neg |
17 | ACC | Whipple | M | 79 | 36 | 2 | 0 | 0 | 1b | Pos (82% loss of 5’ signal) | Neg | Neg |
18 | ACC | Distal pancreas | M | 73 | 35 | 2 | 0 | 0 | 1b | Neg | Neg | Neg |
19 | ACC | Distal pancreas | M | 73 | 23 | 2 | 0 | 0 | 1b | Neg | Neg | Neg |
20 | ACC | Core biopsy | M | 32 | 1 | 4 | Neg | Neg | Neg | |||
21 | ACC | Whipple | M | 59 | 14 | 1 | 0 | 0 | 1a | Neg | Neg | Neg |
22 | ACC | Core biopsy | M | 80 | 0 | Neg | Neg | Neg | ||||
23 | ACC | Core biopsy | F | 53 | 1 | 4 | Neg | Neg | Neg | |||
24 | ACC | Distal pancreas | M | 68 | 37 | 2 | 0 | 0 | 1b | Neg | Neg | Neg |
25 | ACC | Distal pancreas | M | 54 | 48 | 3 | 1 | 0 | 2b | Neg | Neg | nd |
26 | ACC | Distal pancreas | M | 68 | 190 | 3 | 0 | 0 | 2a | Neg | Neg | nd |
27 | ACC | Whipple | M | 46 | 33 | 3 | 1 | 0 | 2b | Neg | Neg | nd |
28 | ACC-NEC | Whipple | M | 67 | 40 | 3 | 1 | 0 | 3 | Neg | Pos (loss of 5’ signal) | nd |
29 | ACC-NEC | Core biopsy | M | 53 | x | 1 | 1 | 4 | Pos (93% split 5’/3’ signals) | nd | nd | |
30 | ACC | Liver excision | F | 29 | 0 | 0 | 1 | 4 | Pos (100% loss of 5’ signal) | nd | nd |
