Table 4 Multivariate analysis of immune cell position according to clinicopathological characteristics.

From: Immune response and stromal changes in ductal carcinoma in situ of the breast are subtype dependent

 

Immune cell position (n = 131)

Touching* (n = 47)

Intraductal* (n = 30)

OR

95% CI

P-value

OR

95% CI

P-value

Age

0.96

0.93–0.99

0.013

0.97

0.93–1.02

0.207

Size (missing n = 17; cm)

1.05

0.92–1.20

0.472

1.17

0.99–1.39

0.067

Growth pattern

1.84

1.10–3.08

0.020

1.57

0.77–3.19

0.216

Grade

1.41

0.75–2.63

0.287

0.57

0.26–1.26

0.161

Calcification

0.87

0.40–1.89

0.723

0.74

0.26–2.13

0.577

Comedonecrosis

0.32

0.16–0.64

0.001

0.58

0.21–1.56

0.280

IHC DCIS subtype (missing n = 3)

1.05

0.75–1.47

0.776

1.29

0.80–2.09

0.300

Ipsilateral recurence (missing n = 5)

0.64

0.11–3.74

0.620

0.94

0.09–9.09

0.956

  1. OR odds ratio.
  2. *Periductal immune cell position set as reference variable (n = 54).
  3. Statistically significant p-values are in bold.