Table 2 Comparison of the most recent hematological changes in 38 CML cases by disease phases (CP-CML vs. AP-CML + BP-CML).

From: Chronic myeloid leukemia with insertion-derived BCR–ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis

 

CP-CML (n = 28)

AP-CML + BP-CML (n = 10)

p values

General

  M/F

12/16

6/4

0.19

  Age: mean (range) (y)

46 (12–78)

53 (40–72)

0.27

BM

  Blast: mean (range) (%)

1 (0–2)

39.7 (0–85)

<0.0001

  Granulocytes: mean (range) (%)

29.6 (12–53)

17.8 (0–64)

0.026

PB

  Blast: mean (range) (%)

0

24.6 (0–91)

<0.0001

  WBC: mean (range) (K/uL))

9.1 (2–77.9)

10 (0.1–31.4)

0.87

  Neutrophils: mean (range) (%)

59 (18.3–83)

44.6 (0–76)

0.043

  Hb: mean (range) (gm/dL)

13.4 (10.5–17)

9.3 (7.3–11.1)

<0.001

  Platelet: mean (range) (K/uL)

223 (51–583)

102 (60–559)

0.032

  1. M male, F female, y years, CP-CML chronic phase CML, AP-CML accelerated phase CML, BP-CML blast phase CML, BM bone marrow, PB peripheral blood, WBC white blood cells, Hb hemoglobin.
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