Table 3 LEF1 and β-catenin expression by immunohistochemistry in primary and metastatic acral melanoma.

From: TERT amplification but not activation of canonical Wnt/β-catenin pathway is involved in acral lentiginous melanoma progression to metastasis

H-score

Primary acral melanomas (n = 34), no. (%)

Metastatic acral melanomas (n = 20), no. (%)

P

β-catenin

  <50

4 (11.8)

7 (35)

0.017

  50–100

14 (41.2)

9 (45)

  >150

16 (47.1)

4 (20)

LEF1

  <50

17 (50)

11 (55)

>0.05

  50–100

6 (41.2)

7 (35)

  >150

11 (32.4)

2 (10)

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