Fig. 2: Heterozygous/dispermic partial hydatidiform mole. | Modern Pathology

Fig. 2: Heterozygous/dispermic partial hydatidiform mole.

From: Heterozygous/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease

Fig. 2

Morphological features of an early partial mole with marked villous hydrop, subtle abnormal trophoblastic proliferation, and irregular villous contour (a). P57 immunohistochemistry shows retained nuclear expression in villous cytotrophoblast and stromal cells (b). STR genotype shows the presence of two paternal allelic copies at multiple loci (c): upper panel—chorionic villi, asterisk indicates two distinct paternal alleles at D13S317 locus; lower panel—paired gestational endometrium.

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