Table 3 Cox regression analysis for biochemical recurrence-free survival in Gleason score 8 patients.
Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
HRa | 95% CI | P value | HR | 95% CI | P value | |
Age (years) | 1.0 | 0.9–1.0 | 0.18 | 1.0 | 0.9–1.0 | 0.05 |
PSA (ng/ml) | 1.0 | 1.0–1.0 | 0.43 | 1.0 | 1.0–1.0 | 0.23 |
pT-stage | ||||||
T2 | ref | ref | ||||
T3a | 2.1 | 1.1–3.8 | 0.02 | 1.8 | 1.0–3.4 | 0.06 |
T3b/T4 | 4.6 | 2.5–8.5 | <0.001 | 4.4 | 2.1–9.3 | <0.001 |
Gleason score | ||||||
3 + 5 | ref | ref | ||||
4 + 4 | 1.9 | 1.1–3.1 | 0.02 | 1.7 | 1.0–2.9 | 0.07 |
5 + 3 | 1.1 | 0.5–2.4 | 0.78 | 1.5 | 0.6–3.6 | 0.37 |
Positive surgical margins | 1.4 | 0.8–2.2 | 0.21 | 0.8 | 0.5–1.5 | 0.55 |
Pelvic lymph node metastasis | 11.8 | 5.6–25.2 | <0.001 | 9.9 | 4.2–23.5 | <0.001 |
Cribriform architecture | 2.4 | 1.4–4.1 | 0.003 | 2.0 | 1.0–3.7 | 0.04 |
