Table 4 Cox regression analysis for metastasis-free survival in Gleason score 8 patients.
Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
HRa | 95% CI | P value | HR | 95% CI | P value | |
Age (years) | 1.0 | 0.9–1.1 | 0.80 | 1.0 | 0.9–1.1 | 0.52 |
PSA (ng/ml) | 1.0 | 1.0–1.0 | 0.96 | 1.0 | 0.9–1.0 | 0.50 |
pT-stage | ||||||
T2 | ref | ref | ||||
T3a | 2.7 | 1.2–6.2 | 0.02 | 2.5 | 1.0–6.7 | 0.06 |
T3b/T4 | 2.4 | 1.0–6.0 | 0.06 | 1.3 | 0.4–3.8 | 0.67 |
Gleason score | ||||||
3 + 5 | ref | ref | ||||
4 + 4 | 3.8 | 1.8–8.1 | 0.001 | 2.4 | 1.0–5.9 | 0.05 |
5 + 3 | 1.1 | 0.32–4.0 | 0.85 | 0.7 | 0.2–3.0 | 0.65 |
Positive surgical margins | 1.0 | 0.5–2.0 | 0.95 | 1.1 | 0.5–2.4 | 0.84 |
Pelvic lymph node metastasis | 11.5 | 5.2–25.9 | <0.001 | 15.0 | 5.6–40.0 | <0.001 |
Cribriform architecture | 6.7 | 2.0–21.9 | 0.002 | 3.5 | 1.0–12.3 | 0.05 |
