Fig. 1: IGF2BP1 is de novo expressed in ATC.
From: IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma diagnosis
a Principle component (PC) analysis on RNA-seq data derived from the test cohort, including 10 ATC, 6 PTC, 6 FTC, and 6 NT samples. b Dot plot presentation of cancer hallmark gene sets upon a GSEA for differentially expressed genes for 10 ATCs vs 18 noATCs (6 PTC, 6 FTC, and 6 NT samples), investigated in (a). NES = normalized enrichment score. c Volcano plot of log2 mRNA fold changes plotted against the −log10 FDR (false discovery rate) for 10 ATCs versus 18 noATCs, investigated in (a). Horizontal dashed line indicates threshold (false discovery rate, FDR ≤ 0.01). Indicated in red are the top 20 ATC-exclusive genes, identified as described in the text.
