Fig. 2: IGF2BP1 protein expression is detectable by Western blot and IHC in ATC samples.
From: IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma diagnosis
a Representative Western blot analysis of indicated proteins in two ATC-derived cell lines (C643 and 8305C) and protein lysates of individual samples analyzed by RNA-seq in (a). VCL served as loading control. b Scatter dot plot presentation of quantified log2 protein expression, determined for test cohort samples, investigated in (a). c IGF2BP1 expression analyzed by immunohistochemistry in representative samples investigated in (a). HE, hematoxylin eosin staining. Scale bars, 100 µm. Statistical significance was determined by Mann–Whitney test in (d) (***p ≤ 0.001; *p ≤ 0.05; n.s. not significant).
