Table 3 Comparison of CPS between three PD-L1 immunohistochemical assays using cutoffs of ≥1 and ≥20.

From: Comparison of three PD-L1 immunohistochemical assays in head and neck squamous cell carcinoma (HNSCC)

Cutoff: ≥1

Kappa (CI)

  22C3 pharmDx vs. SP263

0.22 (0.13–0.32)

  22C3 pharmDx vs. 22C3 LDT

0.43 (0.29–0.56)

  SP263 vs. 22C3 LDT

0.21 (0.066–0.36)

Cutoff: ≥20

 22C3 pharmDx vs. SP263

0.26 (0.10–0.42)

 22C3 pharmDx vs. 22C3 LDT

0.64 (0.42–0.85)

 SP263 vs. 22C3 LDT

0.47 (0.31–0.64)

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