Fig. 2: Histomorphology of the scrotal, para-rectal, and two renal tumors. | Modern Pathology

Fig. 2: Histomorphology of the scrotal, para-rectal, and two renal tumors.

From: Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts

Fig. 2

The superficial scrotal tumor (case 3) shows mildly infiltrative border (A) and is composed of compact spindle cells in storiform pattern (B), mimicking dermatofibrosarcoma protuberans. The para-rectal tumor (case 4) shows solid sheets of ovoid cells (C) with vesicular chromatin and indistinct cell border, accompanied by microcystic spaces (D). Case 5 shows vague fascicular pattern (E) and areas with increased pleomorphism and hyperchromasia (F). Case 6 displays sheets of ovoid cells with variation in cellularity (G). Epithelioid cells were observed in the second recurrent lesion (H).

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