Table 1 Clinicopathologic and molecular information of the cases.
Case# | Age | Sex | Location | Max. dimension | Tumor border | Mitosis | Necrosis | Resection Margin | Positive immunostaininga | Follow-up (weeks) | OncoScan-inferred karyotypeb | FISH-derived average copy number: chr# (copy number) | Note |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 38 | M | Thigh | 6.8 cm | Encapsulated | 2/50 HPF | Present | Close (<1 mm) | Desmin, SMA, MyoD1, myogenin | NED (9) | 54, X, +X, −Y, +5, +5, +12, +12, +20, +20, +22, +22 | Chr5q (3.225), Chr9 (1.75), Chr12 (2.825), Chr13 (1.675), Chr17 (1.625), Chr18q (1.5), Chr20q (3.025), Chr22q (3.325) | Trauma 1 year before |
2 | 35 | F | Hip | 11 cm | Encapsulated, focally infiltrative | 1/50 HPF | Present | Positive | Desmin, MyoD1, myogenin | NED (6) | 46, XY (with a gain of 5q14.3-q35.3) | Chr5q (3.3), Chr9 (1.95), Chr12 (1.9), Chr17 (1.9), Chr18q (1.875), Chr20q (1.775), Chr22q (1.85) | Adjuvant radiotherapy |
3 | 23 | M | Thigh | 7.2 cm | Encapsulated | 5/50 HPF | Absent | Close (<1 mm) | Desmin, SMA, MyoD1, myogenin | NED (146) | 52, XY, +X, +Y, +5, +5, +22, +22 | Not performed | Adjuvant radiotherapy. Previously reported (ref. 6) |
4 | 18 | M | Back | 5.3 cm | Encapsulated, focally infiltrative | 2/50 HPF | Absent | Close (<1 mm) | Desmin, SMA, MyoD1, myogenin | NED (6) | 58, XY, +X, +Y, +5, +5, +18, +18, +20, +20, +21, +21, +22, +22 | Not performed | Neurofibromatosis type 1 |
