Fig. 4: Copy number profiling of myxoid pleomorphic liposarcomas.

A Copy number profile of a representative myxoid pleomorphic liposarcoma tumor. Dots are bins for which copy number is inferred, whereas horizontal graph lines represent segments of predicted equal copy number. The Y-axis indicates the ratio between the observed over the expected number of reads. B Overview of aberrations detected in myxoid pleomorphic liposarcomas. The wave-like figure represents fractions of aberrant samples across the human genome. Patterns above the y = 0 line indicate gains, whilst opposite contours represent losses (e.g., when the top of the wave is at 50%, 50% of samples have a gain at the corresponding locus; when the bottom of the wave is at 10%, 10% of samples have a loss at the corresponding locus). The middle graph line represents mean log₂ ratio, as in (A), corresponding to the right-hand axis.