Fig. 5: Expression of K7 and p16 in hepatocytes and ductules of FNH. | Modern Pathology

Fig. 5: Expression of K7 and p16 in hepatocytes and ductules of FNH.

From: Senescence markers in focal nodular hyperplasia of the liver: pathogenic considerations on the basis of immunohistochemical results

Fig. 5: Expression of K7 and p16 in hepatocytes and ductules of FNH.The alternative text for this image may have been generated using AI.

A, B Comparison of K7 and p16 expression in FNH (immunohistochemistry using antibodies to K7 (A) and p16 (B), respectively, in consecutive sections). Antibodies to K7 (A) react in addition to ductules with hepatocytes in circumscribed areas (asterisks), whereas p16 antibodies (B) decorate only ductular cells. C Ballooned hepatocyte with MDB (arrow; H&E). D Macrovesicular steatosis and group of ballooned hepatocytes (asterisk) expressing cytoplasmic and nuclear p16 and containing p16-positive MDBs. E MDB-containing p16-positive hepatocyte is shown at higher magnification (arrow).

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