Table 2 Comparison of specific types of dysplastic morphologic features of myelodysplastic/myeloproliferative neoplasms-unclassifiable with and without isolated i(17q).
MDS/MPN-U with iso(17q) | MDS/MPN-U without i(17q) | P | MDS/MPN-U with iso(17q) | MDS/MPN-U without i(17q) | P | |
|---|---|---|---|---|---|---|
Lineage | >10%/≥1 | >50%/≥3 | ||||
Erythroid | ||||||
Megaloblastoid changes | 6/8 | 9/13 | 1 | 0/8 | 2/13 | 0.5048 |
Multinucleation | 0/8 | 0/13 | 1 | 0/8 | 0/13 | 1 |
Nuclear contour irregularities | 3/8 | 5/13 | 1 | 0/8 | 0/13 | 1 |
Pyknosis | 0/8 | 2/13 | 0.505 | 0/8 | 0/13 | 1 |
Ring sideroblasts | 1/8 | 3/13 | 1 | 0/8 | 2/13 | 0.5048 |
Myeloid | ||||||
Abnormal nuclear shape | 6/8 | 5/13 | 0.183 | 3/8 | 1/13 | 0.3002 |
Pseudo-Pelger–Hüet nuclei | 6/8 | 3/13 | 0.032 | 3/8 | 0/13 | 0.0815 |
Cytoplasmic hypogranulation | 6/8 | 12/13 | 0.531 | 2/8 | 2/13 | 0.5308 |
Megakaryocytic | ||||||
Micromegakaryocytes | 2/8 | 1/12 | 0.537 | 0/8 | 0/12 | 1 |
Hypolobated/monolobated nuclei | 5/8 | 2/10 | 0.062 | 0/8 | 0/12 | 1 |
Separated nuclear lobes | 1/8 | 3/12 | 0.642 | 0/8 | 1/12 | 1 |
