Fig. 3: Variations in the nuclear and architectural features of the tumors. | Modern Pathology

Fig. 3: Variations in the nuclear and architectural features of the tumors.

From: Oncocytic renal neoplasms with diffuse keratin 7 immunohistochemistry harbor frequent alterations in the mammalian target of rapamycin pathway

Fig. 3

These included: abundant fine granular eosinophilic cytoplasm with round to oval nuclei, resembling what has been described in LOT (A). Occasional tumors showed minor perinuclear clearing (B). Minor nuclear membrane irregularity was noted in a subset of cells (C), and some tumors showed degenerative nuclear atypia, as seen in some oncocytomas (D).

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