Table 1 Patients’ characteristics, clinical features, and malignant transformation.

From: Characterization of initial/early histologic features of proliferative leukoplakia and correlation with malignant transformation: a multicenter study

 

N (%)

Sex

 Female

44 (74.6)

 Male

15 (25.4)

Age (median [range])

65 (27-86)

Smoking status

 Never

33 (57.9)

 Former

23 (40.4)

 Median (mean) pack/year

11.75 (20.6)

 Current

1 (1.8)

 Unknowna

2 (NA)

Clinical appearance

 Smooth leukoplakia

16 (34.8)

 Fissured leukoplakia

15 (32.6)

 Verrucous leukoplakia

6 (13.0)

 Erythroleukoplakia

9 (19.6)

 Unknowna

13 (NA)

Lesions contiguity

 Contiguous

11 (18.6)

 Non-contiguous

48 (81.4)

Family history of cancer

 Yes

33 (86.8)

 No

5 (13.2)

 Unknowna

21 (NA)

Personal history of cancer

 Yesb

14 (28.6)

 No

32 (71.4)

 Unknowna

10 (NA)

  1. NA not applicable.
  2. aUnknown parameters were excluded from percentage calculations.
  3. bFour leukemia, three breast cancers, two myelodysplastic syndromes, and one each of mantle cell lymphoma, carcinoid tumor, lung adenocarcinoma, papillary thyroid carcinoma, prostate cancer, stomach cancer, and rectal adenocarcinoma.
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