Fig. 3: Representative images of TissueCypher. | Modern Pathology

Fig. 3: Representative images of TissueCypher.

From: Utility of ancillary studies in the diagnosis and risk assessment of Barrett’s esophagus and dysplasia

Fig. 3

A–D show a NDBE biopsy from a 66-year-old man with 8-cm BE segment and who was diagnosed with EAC at a surveillance endoscopy 3.9 years later (progressor). TissueCypher scored this specimen high risk. E–H show a NDBE biopsy from a 69-year-old man with 11-cm BE segment with 5.6 years surveillance data showing no progression (non-progressor). TissueCypher scored this specimen low risk. A and E show p16-green, AMACR-red, and p53-yellow; B and F show CD68-green and COX-2-red; C and G show HIF-1α-green and CD45RO-red; D and H show HER2-green and CK20-red. Nuclei labeled by Hoechst are shown in blue in all panels.

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