Fig. 1: Index case of a patient with CNS choriocarcinoma.
From: PD-L1 and PD-1 expression in pediatric central nervous system germ cell tumors
A H&E section showed atypical cells with angulated large nuclei and eosinophilic cytoplasm, in keeping with choriocarcinoma. B Beta-HCG diffuse immunoexpression. C PD-L1 immunostain diffusely positive in the tumor cells. D Pre- and post-checkpoint inhibitor therapy MRI showing tumor response.
