Table 2 Distribution of MMR staining patterns.
Affected MMR Genes | IHC staining | Expected IHC pattern | Numer of cases (n = ) | |||
|---|---|---|---|---|---|---|
MLH1 | MSH2 | MSH6 | PMS2 | |||
MLH1 | − | + | + | − | YES | 5467 |
MSH2 | + | − | − | + | YES | 1653 |
MSH6 | + | + | − | + | YES | 770 |
PMS2 | + | + | + | − | YES | 517 |
Total | 8407 | |||||
MLH1 | − | + | + | + | NO | 172 |
MSH2 | + | − | + | + | NO | 114 |
MLH1 + MSH2 | − | − | + | + | NO | 12 |
Total | 298 | |||||
