Table 1 Clinicopathologic features of Mullerian adenosarcomas.
Case | Age | Grade | Anatomic site | Size (cm)a | Sarcomatous overgrowth | Heterologous elements | Glandular component | FIGO Stage | Clinical follow-up |
|---|---|---|---|---|---|---|---|---|---|
MA01 | 44 | Low | Ovary, arising from endometriosis | 7.8 | No | No | Non-atypical hyperplasia | N/A | NED (25 months) |
MA02 | 72 | Low | Rectovaginal septum | 5.5 | No | No | Atrophic endometrium | N/A | DOD (high-grade recurrence in colonic serosa at 28 months; death at 44 months) |
MA03 | 58 | Low | Uterine corpus | 2.0 | No | No | Inactive endometrium | IA | NED (29 months) |
MA04 | 52 | Low | Cervix | 4.4 | No | No | Endocervical/ tubal metaplasia | IA | NED (25 months) |
MA05 | 53 | Low | Uterine corpus | 5.3 | No | No | Atypical hyperplasia | IB | NED (49 months) |
MA06 | 49 | Low | Uterine corpus | 3.2 | No | No | Inactive endometrium | IA | NED (35 months) |
MA07 | 60 | Low | Uterine corpus | 0.5 | No | No | Proliferative endometrium | IB | NED (17 months) |
MA08 | 71 | Low | Uterine corpus | 5.7 | No | No | Disordered proliferative endometrium | IB | DOD (high-grade abdominal recurrence at 52 months; death at 69 months) |
MA09 | 51 | Low | Uterine corpus | 4.1 | Yes | No | Atypical hyperplasia | IA | AWED (pelvic recurrence at 5 months; last followup at 8 months) |
MA10 | 44 | High | Uterine corpus | 3.0 | No | No | Inactive endometrium | IA | NED (25 months) |
MA11 | 65 | High | Ovary | 15 | Yes | No | Atypical hyperplasia | IIB | NED (49 months) |
MA12 | 60 | High | Ovary | >30 (fragmented) | Yes | No | Atrophic endometrium | IIIBb | DOD (10 months) |
MA13 | 39 | High | Uterine corpus | N/A (biopsy only) | No | No | Atypical hyperplasia | N/A (biopsy only) | AWED (41 months) |
MA14 | 31 | High | Uterine corpus | 5.5 | Yes | No | Secretory endometrium | IIIAb | DOD (7 months) |
MA15 | 59 | High | Uterine corpus | 4.0 | Yes | Yes (chondrosarc) | Atrophic endometrium | IA | NED (52 months) |
MA16 | 66 | High | Ovary | 12.0 | Yes | Yes (rhabdo) | Atrophic endometrium | IIB | DOD (pelvic, vaginal, colonic recurrence at 28 months, death at 33 months) |
MA17 | 23 | High | Uterine corpus | 6.8 | Yes | Yes (rhabdo) | Inactive endometrium | IB | NED (44 months) |
MA18 | 59 | High | Uterine corpus | 3.8 | Yes | No | Inactive endometrium | IA | NED (30 months) |
MA19 | 40 | High | Uterine corpus | 3.5 | Yes | Yes (rhabdo) | Proliferative endometrium | IVA | AWED (vaginal recurrence within 1 month; last followup at 12 months) |
MA20 | 68 | High | Uterine corpus | 17.1 | Yes | Yes (rhabdo) | Atrophic endometrium | IIIB | DOD (abdominal, peritoneal recurrence at 2 months; death at 8 months) |
MA21 | 63 | High | Uterine corpus | 6.5 | No | No | Atrophic endometrium | IA | NED (7 month) |
MA22 | 56 | High | Uterine corpus | 1.8 | Yes | Yes (rhabdo) | Inactive endometrium | IA | NED (1 month) |
MA23 | 76 | High | Uterine corpus | 5.5 | Yes | No | Inactive endometrium | IB | NED (1 month) |
MA24 | 48 | Focal high | Uterine corpus | 2.4 | No | No | Inactive endometrium | IB | NED (12 months) |
MA25 | 43 | Focal high | Cervix | 1.2 | No | Yes (rhabdo) | Endocervical | IA | NED (34 months) |
MA26 | 41 | Focal high | Cervix | 4.5 | Yes | No | Endocervical | IB | DOD (vaginal, chest wall recurrence at 15 months, death at 43 months) |
MA27 | 60 | Focal indeterminate | Uterine corpus | 7.0 | No | No | Atypical hyperplasia | IA | NED (46 months) |
